SYNTHESIS AND CHARACTERIZATION OF ACTIVELY HER-2 TARGETED FE3O4@AU NANOPARTICLES FOR MOLECULAR RADIOSENSITIZATION OF BREAST CANCER

Synthesis and characterization of actively HER-2 Targeted Fe3O4@Au nanoparticles for molecular radiosensitization of breast cancer

Introduction: The present study was done to assess the effect of molecularly-targeted core/shell of iron oxide/gold nanoparticles (Fe3O4@AuNPs) on tumor radiosensitization of SKBr-3 breast cancer cells.Methods: Human epidermal growth factor receptor-2 (HER-2)-targeted Fe3O4@AuNPs were synthesized by conjugating trastuzumab (TZ, Herceptin) to PEGyla

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Smoking associates with distinct clinical phenotypes in patients with systemic lupus erythematosus: a nationwide Danish cross-sectional study

Objectives SLE displays large clinical heterogeneity that beyond genetic factors may be determined by environmental exposures.In this Danish nationwide study, we aimed to determine if clinical subsets of SLE were associated with smoking history.Methods At each of six participating centres, incident or prevalent inpatients and outpatients with SLE w

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